Researchers Say Alzheimer’s Proteins Move from Blood to Accumulate in the Brain


According to the recent experiment made on mice, the proteins related to Alzheimer’s disease can move from blood to occupy the portion of brain. The findings are published in the Molecular Psychiatry, a scientific journal by the Nature Publishing Group.

A neurobiologist, Mathias Jucker from the University of Tübingen in Germany, suggests that the amyloid-beta protein outside the brain may lead to the Alzheimer’s disease. this 9is the more expansive view of Alzheimer’s that may help scientists to invent more treatments that aim parts of the body that are easy to access than the brain.

The long-term inflammation in the brain that damaging tissues may be also caused by the microglia, the cells build-up, while in the healthy brain the same cells inundate and destroy toxins as well as waste. However, in a case of Alzheimer’s patients, microglia can’t clear away these scrap that may include amyloid plaques or toxic tau tangles. Then the body activates large number of microglia to try cleaning off these wastes, which then causes inflammation. The chronic or Long-term inflammation damages the brain cells particularly and ultimately makes the brain cells dead.

Since, the experiments do not state that the Alzheimer’s disease can’t be contracted from the blood of another person. John Collinge, a neurologist from the University College London stated that, “The bottom line is that this study is thought-provoking but shouldn’t cause alarm. There really isn’t any evidence that you can transmit Alzheimer’s disease by blood transfusion.”